| Date | Home | Away | Result |
|---|---|---|---|
| 3/13/25 12:45 PM | FC Lugano | NK Celje | 6-7a.PSO |
| 3/13/25 12:45 PM | KSV Cercle Brügge | Jagiellonia Bialystok | 2-0 |
| 3/13/25 12:45 PM | Djurgardens IF | Pafos FC | 3-0 |
| 3/13/25 12:45 PM | SK Rapid Wien | FK Borac | 2-1a.e.t |
| 3/13/25 3:00 PM | Fiorentina | Panathinaikos Athens | 3-1 |
| 3/13/25 3:00 PM | Chelsea FC | FC Copenhagen | 1-0 |
| 3/13/25 3:00 PM | Legia Warschau | Molde FK | 2-0a.e.t |
| 3/13/25 3:00 PM | Vitoria Guimaraes | Real Betis Sevilla | 0-4 |